From left to right, these represent temperature, rest, drink, and food. On the bottom left corner of the screen, you will find four dials.

If you have played Episode 3 of Wintermute and know the region, it should be survivable. It also doesn't have any fishing, eliminating one potential food source.

For new players, it's likely best to start in one of the four regions below. When you start a new game of The Long Dark in any difficulty other than Interloper, you will be given a choice of regions you can start in, which will greatly affect the initial difficulty of the survival experience.